Next Generation Sequencing Interest Group

In the Next Generation Sequencing (NGS) Interest Group, researchers and bioinformaticians working with NGS data share best practices and foster collaborations.

  • Contact Leon Mei if you wish to join this Interest Group or have question.

Because NGS technology is applied in different sectors, ranging from human medicine to plant genomics, this Interest Group covers a wide range of topics:

  • genomic variants analysis (e.g., SNP, SV, CNV, fusion-gene, variant sharing/filtering),
  • functional genomics (e.g., RNAseq, methylome, ChIP-seq, QTLs, Chromatin Conformation-seqs),
  • clinical-oriented (e.g., pedigree-based analysis),
  • cancer genomics (e.g., cell heterogeneity, pathway),
  • de novo assembly,
  • metagenomics (ref to,
  • new generation of NGS technology (e.g., Nanopore, optical mapping),
  • production pipeline (e.g., reproducibility, scalability, computing and storage infrastructure best practice),
  • NGS data integration: integrate data from different sources (transcriptomics, proteogenomics, epigenetics).

NGS meetings and trainings

The NGS Interest Group organises meetings and supports trainings and multi-center projects.

  • DTL focus meetings that target at a specific topic,
  • NGS PI meetings once every half year for PIs to share project updates, future plans to gain synergy,
  • NGS programmer meet-ups every two months to discuss hands-on problems (during the walk-in hours at the bi-monthly DTL programmers meetings),
  • NGS courses offered via the BioSB research school,
  • Fostering local NGS Community to support ELIXIR, NFU’s Data4lifesciences, BBMRI, Hartwig, FAANG etc.

NGS Interest Group members

This interest group is ran by a core team with the following members:

  • Hendrik-Jan Megens (WUR)
  • Harmen van de Werken (Erasmus MC)
  • Victor Guryev (UMCG)
  • Christian Gilissen (UMCN)
  • Christian Rausch (VUMC)
  • Ies Nijman (UMCU)
  • Lars Eijssen (Maastricht University)
  • Remco Ursem (RijkZwaan)
  • Leon Mei (LUMC, chair)

Please join us

If you want to become a member of the NGS Interest Group, you should:

  • be people working in the Netherlands, in the public or private sector,
  • be interested in bioinformatics analysis of NGS data,
  • have reasonable hands-on experience,
  • contact Leon Mei.