On Thursday February 8, there will be a very interesting one-day postgraduate course entitled ‘Analysis tools to understand metabolic networks’. The course will be given by Prof. Jannie Hofmeyr from the Centre for Complex Systems in Transition and Dept. of Biochemistry, Stellenbosch University, Stellenbosch, South Africa.
Date: 8 February 2018
Costs: Free of charge
Background
For the aim of understanding the often complex regulation of cellular metabolism, computational systems biology develops mathematical models that simulate metabolic processes. A good metabolic model is extremely valuable for gaining a deep understanding of the behaviour of metabolic processes, for studying aspects of metabolic control and regulation, for finding potential drug targets and testing prospective drugs, for designing biotechnological interventions, and for answering general what-if questions. However, as anyone who has attempted such model-building knows, the development and validation of an accurate kinetic metabolic model is a huge task, especially if the kinetic data for the enzymes involved have to be determined experimentally. Because of this, just developing and publishing the model is where it often ends, and very little is actually done with the model afterwards. A major reason is that the deep analysis of a kinetic model, whether your own or someone else’s, needs theoretical and computational tools. This 1-day course will introduce you to the theory and ways of thinking about metabolic networks, and to a suite of corresponding tools and their use.
Target audience:
PhD students and postdocs. AIMMS members will get priority.
Credits:
VU and AIMMS PhD students can get 1 EC for this course. You will receive a certificate of attendance.
