This course is organised in collaboration with Dr. J.T. den Dunnen, Human Genetics & Clinical Genetics, LUMC, Leiden
Aim of the course:
DNA sequencing, incl. NGS, is a standard technology used in most modern laboratories. When the focus is on the identification of variants in the sequence, the next challenge is to evaluate these variants and their potential consequences. The “Variant Effect Prediction” course has been developed to show what one can do to predict the consequences on DNA, RNA and protein level, i.e. to classify the variants
This course has been developed for technicians and PhD students working in a DNA laboratory (e.g. research and clinical diagnostic laboratories) who are involved in DNA sequencing data analysis. Participants are expected to bring their own laptop (PC or Mac) as this will be needed for the Course. Participants can bring their data/from an article for some of the practical sessions.
We offer a four-day course consisting of a series of lectures on variants and variant effect prediction on both the DNA, RNA and protein level. Furthermore, we will show how these variants can be viewed in genome browsers, and give an overview of variant effect prediction software and including “hands-on” data analysis practicals. All participants will receive a course manual.