The latest human reference genome GRCh38 (previously also known as hg20) has been released for one year now. Although most NGS teams are still working with hg19, some groups did investigate and test the new GRCh38 genome. As part of this meeting, we will learn from their experience and problems they encountered in using GRCh38.
There will be also lots of time for discussion and we want to focus on two aspects:
- tooling discussion on how to handle multiple references, annotation tools etc and
- a more biological one: improvements, comparisons to hg19, new insights on using hg20 to improve the research and clinical output.
Bioinformaticians who have been working with NGS data for at least one year. You must have working experience with NGS reads alignment, quality assessment, annotation, gene differential expression analysis in order to join the meeting.
Date: March 31st 2015, 13:00 – 15:30
Venue: SURF (new location), Kantoren Hoog Overborch (Hoog Catharijne), Moreelsepark 48, 3511 EP Utrecht
The preliminary programme is available at the DTL wiki.
The meeting is free of charge but registration is required. Please register by adding your name to the list on the DTL wiki page or by sending an e-mail to Leon Mei.