Systematic integrative genomics, transcriptomics and ultra-deep proteomics analysis reveals novel insight in disease biology
Experts in proteomics from Utrecht University and next-generation DNA sequencing from the Hubrecht Institute/UMC Utrecht collaborated in a study to systematically determine the consequences of genetic variation on the transcriptome and proteome. The researchers applied ultra-deep quantitative proteomics, whole genome sequencing and RNA-seq to liver tissues from different inbred rat strains. One of these inbred rats, the spontaneously hypertensive rat… Continue reading