Netherlands Cancer Institute (NKI)
Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Dr. H.G.A.M. van Luenen
0031 (0)20 5122097
The Netherlands Cancer Institute is an independent research organization focussing on basic, translational and clinical cancer research in close collaboration with the Antoni van Leeuwenhoek hospital and other national and international research organizations.
The NKI harbours 55 research groups that all push the boundaries of life science in general and cancer research specifically. To mention only a few groups: Ton Schumacher develops innovative tools for analysing complex populations of immune cells, Daniel Peeper develops the introduction of human xenographs in mice to predict disease development and treatment outcome, Jos Jonkers develops state-of-the-art mouse model systems for cancer, Anton Berns is developing improved ways of making complex genetically modified mouse models for cancer, Bas van Steensel and Fred van Leeuwen are developing new methods to probe the chromosomal organization, Reuven Agami is developing tools for RNAi; Rene Bernards and Roderick Beijersbergen are developing high throughput screens and targeted screens to identify new targets and treatment modalities for the clinic, Jan Jakob Sonke is improving radiotherapy by better imaging and image guided adjustment of the therapy, Floor van Leeuwen develops large databases of cancer patient cohorts, Kees Jalink is improving light microscopy, and Lodewyk Wessels is developing algorithms to analyze complex data sets.
The NKI also harbours a wide range of research facilities that actively support researchers with state-of-the-art technologies such as: the genomics facility (e.g. next generation sequencing), the screening facility (using chemical and RNAi libraries), the protein facility (using several protein expression systems and different ways to characterize proteins), the mouse cancer clinic (e.g. intervention, imaging, transgenesis and cryopreservation), the mass spec facility (being set up at the moment), the animal pathology facility and the molecular pathology & biobank facility (provides easy access to (anonymous) patient material and data). We also have a excellent technology transfer facility that is (inter)nationally leading. The facilities at the NKI provide service to outside users in an academic setting.
- Biomedical & health
- Cancer cell biology
- Immune and microenvironment response to tumours
- Gene expression regulation in higher and lower eukaryotes
- Signalling pathways in cells (normal and tumour)
- Chromosome stability and DNA damage repair
- Molecular biology
- Life science
Expertise and Track Record
The Netherlands Cancer Institute is the only an independent research organisation closely associated with a cancer hospital in the Netherlands. It has been accredited the status of Comprehensive Cancer Center by the OECI and by peers it is viewed as one of the top international cancer research cents. Having such a large concentration of renowned top researchers and many state-of-the-art central researchers facilities makes the NKI unique.
Cancer Genomics Center, Center for Personalized Cancer Treatment
Centre for Biomedical Genetics
EU consortia like Eurocan and ARTFORCE
Netherlands Bioinformatics Centre
Netherlands Consortium for Systems Biology
Netherlands Proteomic Center
Oncology Graduate School Amsterdam
Organization of European Cancer Institutes
Van Leeuwenhoek Center for Advanced Microscopy
- A complete list of facilities can be found on https://www.nki.nl/facilities/