Hanzeplein 1 9713 GZ Groningen
Prof. dr. A.K. Groen
0031 (0)50 363 2669
The goal of the NWO funded SBC-EMA is to unravel the intricate relationship between metabolism and the biology of ageing. This relationship, which has been conserved throughout evolution, is bidirectional: metabolism affects the ageing of an organism, while the metabolic system itself declines under the influence of ageing. Both metabolism and ageing are systems properties that are affected by a large number of processes at the molecular, cellular and organ level. Hence a full understanding of metabolism, ageing and their interaction necessitates a systems biology approach.
We use the budding yeast Saccharomyces cerevisiae and the mouse as model organisms. With an interdisciplinary team of scientists, we will use various approaches of systems biology.
- Systems biology
- Yeast, mouse and human metabolism