Contact Details
UMC Utrecht
UMC Utrecht, Lundlaan 6, 3584EA Utrecht
Dr. N.M. Verhoeven Duif en Prof. B. Burgering
0887555317
Hotel Description
The Utrecht Center for Medical Metabolomics is based in the UMC Utrecht, division of Biomedical Genetics. The center unites metabolic knowledge from both the diagnostic laboratory and more fundamental metabolic research. We offer a wide range of analyses for biomedical research and have a great number of collaborations.
- Biomedical & health
- Agri & Food
- Bio informatics
- Metabolism
- Oncology
- Neurology
Expertise and Track Record
Unique analyses:
– Vitamin B6 vitamers
– D-amino acids and other enantiomer-selective analyses
– Krebs cycle & related metabolites platform
– Direct infusion mass spectrometry
Expert knowledge on
– Vitamin B6 metabolism
– Cancer metabolism & regulation
– Amino acid metabolism
– Regulation of energy metabolism
Recent and current projects:
– biochemical characterisation of knock-out mice
– biochemical characterisation of knock-out drosophila
– metabolic studies in zebra fish larvae
We have several projects on the functional characterisation of novel genetic variants that were found by next generation sequencing (whole exome sequencing).
- D-amino acid aberrations in cerebrospinal fluid and plasma of smokers. PMID:23615666
- Development and validation of a quantitative LC-tandem MS assay for hexadeca-4,7,10,13-tetraenoic acid in human and mouse plasma. PMID:23502461
Utrecht Life sciences: provision of metabolomics technology
Hotel Characteristics
- 2 principlal investigators, 4 post docs, 1 bio infomatician, 6 technicians, 1 labamager
5%
- Waters: Xevo with UPLC; UPLC-Ultima. Thermo: Q-exactive plus. & LTQ-Orbitrap-XL; GC-MS
ISO15189
No